Seminar given at the Redwood Center for Theoretical Neuroscience at UC-Berekeley on February 20, 2008. Speaker is Costa Colbert of Evolved Machines, Inc. and Dept. of Biology and Biochemistry, University of Houston.
Spike-timing dependent plasticity has gained much recent attention as a basis for encoding information at synapses. I will present a number of features of back-propagating dendritic spikes in pyramidal neurons that increase the complexity of dendritic information storage. Both electrophysiological recordings of dendritic ion channels and multi-site multi-photon imaging of dendrites will be discussed in relation to a model of compartmentalization of the dendritic arbor.